Protects against hepatitis A and B


  • A virus that affects the liver
  • Causes fever, an upset stomach, tiredness, diarrhea, headache and yellowing of the skin and eyes (called jaundice)
  • Although there are several viruses that cause hepatitis, the two most common are Hepatitis A and Hepatitis B

Hepatitis  A

  • Is spread by not washing your hands properly after going to the bathroom or eating food contaminated with sewage. It can also be spread through sexual contact
  • Risk areas for Hepatitis A include Africa, Asia, Caribbean, Middle East, Central America and South America

Hepatitis B

  • Is spread from person to person by contact with blood, semen, vaginal secretions or possibly saliva of an infected person or items contaminated by these body fluids
  • Hepatitis B is found throughout the world Twinrix ® (Combined Hepatitis A and Hepatitis B) Hepatitis A and B vaccine is a combined vaccine called Twinrix
  • Twinrix is available in two strengths:
    • Twinrix Junior – for people age 1 year to 18 years of age
    • Twinrix – for people aged 19 years of age and older
  • Three doses are required* ​

Who should get Twinrix?

  • It is recommended for those who travel to areas where Hepatitis A and B infections are common
  • People who want combined protection for Hepatitis A and Hepatitis B

Who should not get Twinrix?

  • Children under one year of age
  • People who have had a bad reaction to a vaccine or an ingredient in the vaccine
  • If you are pregnant, talk to your doctor or Public Health Nurse
  • If you are taking medications or have any diseases that lower the immune system or increase bleeding, talk to your doctor or Public Health Nurse
  • If you have had a bad reaction to an antibiotic called neomycin

Is Twinrix safe?

  • Yes. You may have redness, swelling and warmth where the needle went in.
  • Serious reactions to the vaccine are rare (e.g. hives, swelling of the mouth or throat or trouble breathing)
  • Call your doctor if you or your child have any of these problems within 3 days of getting the needle:
    • Hives
    • Crying for more than 3 hours
    • Swelling of your face or mouth
    • Trouble breathing
    • Very pale colour and tiredness
    • High fever (over 39° C or 102.2° F)
    • Convulsions (muscle spasms) or seizures
    • Other serious problems